Dengue fever vector control currently uses chemical larvicides, but the use of chemical larvicides is considered less effective because Ae. aegypti larvae have developed resistance. Berenuk plant (C. cujete) is one of the plants that has potential as a larvicide. The aim of the research was to analyze the effectiveness of C. cujete fruit skin extract and flesh extract as an Aedes aegypti larvicide and to determine the content of active compounds found in the skin and flesh of berenuk fruit. Phytochemical screening of fruit skin extract and fruit flesh extract using thin layer chromatography test. Mortality analysis of Ae. aegypti larvae using Two-way Anova and probit to determine the LC50 value. Research results show that C. cujete fruit skin and flesh extract contained alkaloid, flavonoid and triterpenoid compounds. C. cujete fruit skin extract and flesh extract can cause mortality of Ae. aegypti larvae with LC50 values, namely the concentration of fruit skin extract 3415.007 ppm and fruit pulp extract 3112.767 ppm during 96 hours of observation. Fruit skin extract and fruit flesh extract of C. cujete have larvicidal effect against Ae. aegypti.
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