<![CDATA[Background: Type 2 diabetes mellitus (T2DM) is a chronic disease requiring long-term management. Glycemic control can be influenced by medication adherence, self-care behaviors, family support, and psychological conditions. This study aimed to analyze the relationship between medication adherence, dietary habits, physical activity, family support, and psychological factors and the glycemic control status of T2DM patients at Hospital X. Methods: An observational analytic quantitative study with a case-control design was conducted from May to July 2026. A total of 84 T2DM patients participated, comprising 42 patients with controlled diabetes and 42 with uncontrolled diabetes. Cases were recruited using total sampling, and controls were selected at a 1:1 ratio. Data were collected using questionnaires and medical records. Medication adherence, dietary habits, and physical activity were assessed using the Summary of Diabetes Self-Care Activities (SDSCA); family support was assessed using the Hensarling Diabetes Family Support Scale (HDFSS); and psychological factors were assessed using the Depression Anxiety Stress Scale-21 (DASS-21). Glycemic control status was determined based on HbA1c levels. Relationships were analyzed using Fisher’s Exact Test. Results: Significant associations were found between glycemic control status and medication adherence (p<0.001), dietary habits (p=0.001), physical activity (p<0.001), family support (p=0.009), and psychological factors (p<0.001). In the controlled group, all 42 respondents demonstrated good medication adherence, good dietary habits, good physical activity levels, good family support, and normal psychological conditions. Conversely, all respondents falling into categories of poor adherence, poor diet, inactivity, insufficient support, or psychological distress belonged to the uncontrolled T2DM group. Conclusion: Medication adherence, dietary habits, physical activity, family support, and psychological factors are significantly associated with glycemic control in T2DM patients. Nursing care needs to integrate assessments of treatment adherence, self-care behaviors, family support, and psychological conditions. Conclusion: Medication adherence, dietary patterns, physical activity, family support, and psychological factors are significantly associated with glycemic control in patients with type 2 diabetes mellitus (T2DM). Nursing care needs to integrate assessments of treatment adherence, self-care behaviors, family support, and psychological conditions.]]>
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