Highlights: The incidence of PMPS remained relatively high. Age was a preoperative risk factor for PMPS. Patients who experienced PMPS had higher BMI, although the association was not statistically significant. Abstract Introduction: Surgical intervention is the primary treatment modality for breast cancer but frequently results in chronic neuropathic pain in the anterior chest wall, armpit, and medial upper arm, termed post-mastectomy pain syndrome (PMPS). Prior studies have yielded inconsistent results concerning the impact of age and body mass index (BMI) as preoperative risk factors on the incidence of PMPS. This study aimed to determine the association of age and BMI with the incidence of PMPS among breast cancer patients. Methods: An observational cross-sectional study was performed in the Chemotherapy Center Abdoel Wahab Sjahranie Regional Hospital, Samarinda, Indonesia, in September 2024. Thirty-two female patients who had undergone mastectomy were interviewed using the Pain Detect Questionnaire-Indonesia (PDQ-Ina). The data were analyzed statistically using the International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) version 26.0. The Mann-Whitney test was used in bivariate analyses. Results: Post-mastectomy pain syndrome was identified in 34.4% of patients. The association between age and PMPS was significant (p<0.001). In contrast, no significant association of BMI with PMPS was identified (p=0.059). Conclusion: Post-mastectomy pain syndrome persisted in breast cancer patients who underwent mastectomy, with younger patients experiencing higher rates of PMPS. Although patients with PMPS had a higher BMI, this association was not statistically significant.
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