Highlights: Knowledge and adherence are significantly associated with controlled hypertension. Education and patient-centered care are key to improving adherence and preventing complications. Abstract Introduction: Hypertension is a major risk factor for cardiovascular diseases but can be controlled through improved knowledge and adherence to complication prevention. This study examined the relationship between knowledge, adherence, and controlled hypertension among patients at Taktakan Public Health Center, Serang, Indonesia. Methods: A cross-sectional study was conducted involving 83 hypertensive patients (n=83) selected via consecutive sampling. Data were collected using the Hypertension Knowledge Level Scale (HK-LS) and an adherence questionnaire adapted from Vestabilivy and Rukayah (2014). Data were analyzed using Chi-square tests and odds ratios with the International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) version 27.0. Statistical significance was set at p<0.05. Ethical approval was obtained. Results: Most patients had uncontrolled hypertension (n=59; 71.1%), low-to-moderate knowledge (n=66; 79.5%), and poor adherence (n=54; 65.1%). There were statistically significant associations between knowledge (p=0.018) and adherence (p<0.001) and blood pressure control status. Conclusion: Knowledge and adherence are key to hypertension control. Continuing education and patient-centered approaches are essential to improving adherence and reducing complications.
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