Backgrounds: Chronic Kidney Disease decreases the glomerular filtration rate eGFR <60 ml/minute/1.73 m2 for three months. CKD can cause renal dysfunction, end-stage renal disease, and progression of cardiovascular disease. The increasing prevalence of chronic kidney disease(CKD) affects aging populations. The Elderly frequently present multiple comorbidities leading to polypharmacy and are vulnerable to medication-related problems. Objective: This study aimed to review potential drug-related problems (DRPs) in geriatric patients with advanced CKD. Methods: The research approach is a scoping review, which involves searching for publications published in journals about drug-related difficulties in geriatric patients or elderly with ESRD. Literature searches were conducted through electronic database searches, including PubMed, Science Direct, and Google Scholar. Journals were selected based on inclusion criteria and exclusion criteria. Results: The results led to 5 published journals that indicate DRPs in CKD patients statistically increase along with age due to comorbidities and polypharmacy. Conclusion: The most common DRPs found were inappropriate medication, side effects, non-prescribed drugs, contraindications, and medication prescribing errors. Healthcare providers must reassess each medication prescribed for every elderly patient to minimize the incidence of DRPs.
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