Whole blood (WB), also known as complete blood, is a complete product of blood that contains all its components, such as platelets, erythrocytes, leukocytes, and plasma. The use of whole blood is justified only when the oxygen-carrying capacity and volume expansion required are provided for conditions such as acute bleeding, hypovolemic shock, and major trauma with bleeding of more than 1500 ml. The goal is to find out if whole blood at the Indonesian Red Cross Serang Regency Blood Donation Unit (BDU) has different haemoglobin levels after a 14-day storage period. Using total sampling with a sample size of 40, this study employs an observational analytical type with a quantitative approach and a population of 40. Microsoft Excel and IBM SPSS version 26 were then used to process the data, and the outcomes are displayed as frequency distribution tables, graphs, and percentages. The T-test computation produced a P value of 0.007. The haemoglobin levels in whole blood before storage (day 1) and after storage (day 14) differ significantly, as indicated by the value being less than 0.05. The whole blood (WB) components at the BDU Indonesian Red Cross Serang Regency had different haemoglobin levels before and after 14 days of storage.
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