<![CDATA[Caffeine is a type of alkaloid found in coffee, tea, and chocolate. Caffeine consumption is generally safe and offers benefits such as increased alertness and concentration; however, excessive consumption can potentially lead to caffeine poisoning or overdose, which can be harmful to health and even life-threatening. Analytical determination of caffeine is generally performed using conventional techniques such as HPLC and UV-Vis spectrophotometry. An alternative analytical method with potential, but has not yet been widely explored, is cyclic voltammetry. In this study, a cyclic voltammetry method for caffeine analysis was developed using a working electrode modified with a molecularly imprinted polymer to enhance electrode sensitivity. Bulk polymerization was used to produce the molecularly imprinted polymer (MIP), whose characteristics were then analyzed using SEM and FTIR instruments. The optimal electrode composition was obtained at a ratio of 1:2:2 (KCl: agar powder: MIP), which resulted in a cathodic peak current (Ip,c) of −1.45 × 10−3 A at pH 5. Higher conductivity facilitates easier electron transfer, which in turn results in a higher peak current. The application of this method to the analysis of caffeine in ground coffee types A, B, and C resulted in caffeine contents of 17.46 ppm, 12.87 ppm, and 13.78 ppm, respectively. The voltammetric method showed a limit of detection (LoD) of 2.26 ppm and a limit of quantitation (LoQ) of 7.53 ppm. These results indicate that the molecularly imprinted polymer-modified electrode is an effective tool for analyzing caffeine using the cyclic voltammetry method.]]>
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