Introduction: Pulmonary tuberculosis (TB) is an infectious disease, and one of the risk factors is the low level of community prevention behavior. TB prevention efforts are important in community groups in high-risk places, such as Islamic boarding schools, which have characteristics of dense occupancy and intense interaction among students. This study aims to identify the determinants of TB prevention behavior among students.Methods: The quantitative study type with a cross-sectional study design. The sampling procedure used proportional stratification and obtained 81 students from Al-Ikhsan Beji Islamic Boarding School. Data were collected using a questionnaire through interviews. Data analysis was done through Chi-square tests and Logistic regressions. Results: The TB prevention behavior of most respondents is in a poor category (51.9%). The bivariate analysis revealed that knowledge (p=0.026), perceived benefits (p=0.005), and perceived barriers (p=0.013) were related to TB prevention behavior. The multivariate analysis indicated that knowledge (p=0.049), perceived benefits (p=0.018), and perceived barriers (p=0.043) were significantly associated with TB prevention behavior. Knowledge becomes the strongest factor, with the Odds ratio (OR) of 3.615, indicating that respondents with low knowledge were 3.615 times more likely to fail in adopting TB prevention behavior.Conclusion: Perceived vulnerability, perceived seriousness, and cues to action did not determine the TB prevention behavior of students. Increasing educational messages on TB prevention, collaboration between community health centers, Islamic boarding school caregivers, and the Islamic boarding school health post need to be carried out.
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