Antibacterial activity of ethanol extract of Malay apple leaves (Syzygium malaccense) against Staphylococcus aureus: Uji daya hambat ekstrak etanol daun jambu bol (Syzygium malaccense) terhadap bakteri Staphylococcus aureus

Dela Anggina (Mahasiswa Fakultas Kedokteran Gigi Universitas Baiturrahmah Padang, Padang, Indonesia)
Fitria Mailiza (Bagian Oral Medicine, Fakultas Kedokteran Gigi Universitas Baiturrahmah Padang, Padang, Indonesia)
Netta Anggraini (Bagian Periodontik, Fakultas Kedokteran Gigi Universitas Baiturrahmah Padang, Indonesia)
Dhona Afriza (Bagian Oral Medicine, Fakultas Kedokteran Gigi Universitas Baiturrahmah Padang, Padang, Indonesia)
Fauzia Nilam Orienty (Bagian Konservasi, Fakultas Kedokteran Gigi Universitas Baiturrahmah Padang, Padang, Indonesia)

MDJ (Makassar Dental Journal)
Vol. 15 No. 2 (2026): Volume 15 Issue 2 August 2026

One plant that can be used as an herbal medicine is malay apple leaf (Syzygium malaccense), which is rich in phenolic compounds and flavonoids and pos-sesses antioxidant, anti-inflammatory and antibacterial properties due to its secondary metabolites. This study explored the antibacterial inhibitory activity of MAL ethanol extracts against Staphylococcus aureus. The laboratory experiment was conducted in vitro using a post-test only control group design. The samples consisted of 5%, 10% and 15% MAL ethanol extracts and S.aureus bacteria, with a positive control of 1% clindamycin and a negative control of aquadest; the Kruskal-Wallis test was used, followed by the Mann-Whitney test. The 5% MAL extract yielded an average inhibition zone of 3.9, the 10% ex-tract yielded an average of 5.25, and the 15% extract yielded an average of 5.95; the non-parametric Kruskal-Wallis test yielded a significance value of 0.000<0.05. It was concluded that the inhibitory activity of MAL ethanol extracts against S.aureus at concentrations of 5%, 10% and 15% was weak.