Interest : Jurnal Ilmu Kesehatan
INTEREST: Jurnal Ilmu Kesehatan Volume 15 Issue 2 November 2026

Protein-First Meal Sequence and Blood Glucose Response in Patients with Type 2 Diabetes Mellitus

Vinolia Wahyuning Agustine (Program Studi Sarjana Terapan Gizi dan Dietetika, Politeknik Kesehatan Kemenkes Malang, Indonesia 65119.)
Sutomo Rum Teguh Kaswari (Program Studi Sarjana Terapan Gizi dan Dietetika, Politeknik Kesehatan Kemenkes Malang, Indonesia 65119.)
Dwipajati Dwipajati (Program Studi Diploma 3 Gizi, Politeknik Kesehatan Kemenkes Malang, Indonesia 65119.)



Article Info

Publish Date
07 Sep 2026

Abstract

ABSTRACT Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder requiring appropriate dietary management. Meal-sequence modification, particularly consuming protein before carbohydrates, may help regulate postprandial glucose levels. Methods: This quasi-experimental study involved 26 patients with T2DM selected using non-probability purposive sampling. Participants received two meal-sequence interventions for two weeks: protein before carbohydrates (Intervention A) and protein together with carbohydrates (Intervention B). Group 1 received 40 g of red bean soup, while Group 2 received 22 g of beef soup. FBG and 2h-PBG were measured at each intervention stage and analyzed using the Independent Samples T-Test at a significance level of p < 0.05. Results: After Intervention A, mean FBG was 147.54 ± 19.40 mg/dL in Group 1 and 147.31 ± 26.83 mg/dL in Group 2 (p = 0.980), while 2h-PBG was 193.38 ± 23.45 and 210.31 ± 53.40 mg/dL, respectively (p = 0.306). After Intervention B, mean FBG was 148.31 ± 20.39 and 156.23 ± 24.82 mg/dL (p = 0.383), while 2h-PBG was 189.23 ± 26.94 and 220.92 ± 55.85 mg/dL (p = 0.078), respectively. Conclusion: No significant differences in FBG or 2h-PBG were observed between the plant-based and animal-based protein groups. However, the consistently lower 2h-PBG with red bean consumption suggests a potentially favorable glycemic response warranting further investigation. Meal sequencing may be considered as a complementary dietary strategy alongside appropriate dietary intake and glycemic control.

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Journal Info

Abbrev

int

Publisher

Subject

Health Professions

Description

Jurnal Ilmu Kesehatan Merupakan jurnal yang menyediakan forum untuk bertukar ide tentang teori, metodologi dan isu-isu mendasar yang terkait dengan dunia kesehatan yang meliputi keperawatan, kebidanan, fisioterapi, akupuntur, jamu (herbal), okupasi terapi, ortotik prostetik, terapi wicara, kesehatan ...