Coronary artery disease is one of the non-communicable diseases that lead to the cause of death globally. It not only can disturb of physical, psychological, and social aspects, but also decrease the quality of life (QoL). The perception of QoL is a difference among patients with coronary artery disease. Characteristic demographic can assist patients in identifying and addressing QoL declined. This study examined the relationship between demographic characteristics and quality of life in patients with coronary artery disease. This is a cross-sectional study that reviewed patients with coronary artery disease. Par ticipants were 124 (96 males and 28 females) with purposive sampling. Quality of life was measured with (SF-36) questionnaire. Spearman rho correlation has utilized the relationships between the independent and dependent variables. Spearman rho correlation coefficient analysis indicated that demographic characteristics (age (0.216), gender (0.075), marital status (0.224), and alcohol consumption (0.092)) were not correlated significantly, but education level (0.002), occupation (0.001), income (0.003), and exercise (0.014) were related significantly with quality of life. There was a statistically significant relation ship between demographic characteristics and quality of life in patients with coronary artery disease.
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