<![CDATA[Background: The food system is a complex network that shapes health outcomes across human, animal, and environmental domains. Increasing globalization, agricultural intensification, and environmental changes have amplified risks such as zoonotic diseases and antimicrobial resistance (AMR). The One Health approach provides an integrated framework to address these interconnected challenges. This study aimed to examine the role of One Health in food systems through a literature review of studies published between 2014 and 2025. Methods: Articles were retrieved from PubMed, Scopus, and Google Scholar using relevant keywords. Selected studies were analyzed using a thematic approach focusing on human, animal, and environmental health perspectives. Results: The findings indicate that food systems serve as important pathways for zoonotic disease transmission and the spread of AMR, particularly through intensive livestock production and inappropriate antibiotic use. In addition, food production contributes to environmental degradation, including pollution and greenhouse gas emissions, which further affect health outcomes. Conclusion: Despite increasing recognition of the One Health approach, its implementation remains limited, especially in developing countries. Strengthening interdisciplinary collaboration and integrated policies is essential to improve food system safety, public health, and environmental sustainability.]]>
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