<![CDATA[The rupture rate in abscesses is still high, the presence of rupture in LA will increase the morbidity and mortality rate, the presence of rupture will affect treatment options and affect the length of stay in hospital as well as the potential cost burden for this disease. This study aimed to determine the predictive factors for rupture of liver abscess patients who were hospitalized in Dr. Soetomo Hospital in the period 2011-2017. This study uses a retrospective - single analysis. The target population was patients with liver abscesses who were hospitalized in Dr. Soetomo Hospital Surabaya since January 1, 2011 - July 31, 2017. The study sample was 137 people, sampling was done by consecutive sampling. Analysis of rupture predictive factors was carried out by bivariate test using chi square test and then variables in the bivariate analysis, results p <0.25, entered into multivariate regression analysis logistics to get a rupture predictor factor model. From 138 subjects, LA was more about males than females (4.3:1), with an average age of 44.80 ± 14.98 years, comorbid factors with the most DM, etiology of PLA higher than ALA. The most common complaints of LA are stomach pain and fever. In the rupture group, the proportion of hepatomegaly, pleural effusion, leucocytosis, elevated serum transaminases, hyperbilirubinemia, hypo albumin, giant-single abscess in right lobe was more dominant when compared to the non-rupture group. The proportion of morbidity (sepsis) and mortality in the rupture group was higher than in non-rupture group. Obtained a mortality rate of around 5.79 %, where septic shock is the most dominant cause of death. The magnitude of LA rupture is around 26.81%. The most dominant clinical manifestation of rupture is empyema, peritonitis, pneumonia and peripancreatic abscess. The results of this study indicate the size factor of abscesses and leucocytosis are independent predictive factors for rupture LA]]>
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