Cleft lip is a congenital craniofacial anomaly influenced by multifactorial genetic and environmental factors, and advances in prenatal imaging have significantly improved early detection and treatment preparation. This narrative review aims to synthesize recent evidence from 2015 onward regarding the etiology, early diagnosis, and multidisciplinary management of cleft lip, including the roles of surgery, dentistry, orthodontics, speech therapy, and psychosocial support. Current literature demonstrates that refined surgical techniques have enhanced facial symmetry, functional restoration, and long-term developmental outcomes. Coordinated dental and orthodontic interventions are essential for addressing maxillary deficiencies, dental anomalies, and occlusal development throughout growth. Speech therapy remains crucial in supporting velopharyngeal competence and improving communication skills, while psychosocial guidance plays a significant role in fostering emotional well‑being, social adjustment, and long-term quality of life. Studies consistently emphasize that successful outcomes depend on early diagnosis, continuity of care, and effective collaboration among specialists within a structured cleft team. Evidence supports that optimal cleft lip management is achieved through a comprehensive, individualized, and multidisciplinary approach that integrates surgical, orthodontic, speech, and psychosocial interventions to maximize functional results, aesthetic satisfaction, and overall patient quality of life.
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