<![CDATA[Background: Tuberculosis control requires optimal performance from healthcare workers. Psychosocial factors such as transformational leadership, subjective well-being, and work motivation are believed to play a role in enhancing this performance. This study aims to analyze the effects of transformational leadership and subjective well-being on the performance of healthcare workers in TB control, as well as to examine the role of work motivation as a mediating variable. Subjects and Method: This study employed a cross-sectional design with a sample of 265 health workers at nine community health centers in Sragen Regency, selected using purposive sampling. The independent variables included transformational leadership and subjective well-being; the dependent variable was health worker performance; and work motivation served as the mediating variable. The data were analyzed using path analysis. Results: The results of the study indicate that work motivation has a positive and significant effect on the performance of healthcare workers (b = 1.04; 95% CI 0.63 to 1.45; p<0.001). Transformational leadership also has a positive and significant effect on performance (b=0.36; 95% CI 0.14 to 0.57; p=0.001), while subjective well-being has a positive but not significant effect (b=0.21; 95% CI -0.02 to 0.43; p=0.075). Transformational leadership (b=0.18; 95% CI 0.11 to 0.24; p<0.001) and subjective well-being (b= .38; 95% CI 0.33 to 0.42; p<0.001) have a significant effect on work motivation. Furthermore, work motivation significantly mediated the effects of transformational leadership (b=0.19; 95% CI 0.10 to 0.27; p<0.001) and subjective well-being (b=0.39; 95% CI 0.23 to 0.56; p<0.001) on healthcare workers’ performance. Conclusion: Work motivation and transformational leadership significantly influence healthcare workers’ performance in tuberculosis control, with work motivation serving as the primary mediator linking transformational leadership and subjective well-being to performance.]]>
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