Sistemasi: Jurnal Sistem Informasi
Vol 15, No 9 (2026): Sistemasi: Jurnal Sistem Informasi

XAI Interpretation to Enhance Transparency in Skin Cancer Classification using CNN

Muhammad Abdul Ghofur (Unknown)
Maria Ulfah Siregar (UIN Sunan kalijaga Yogyakarta)
Ahmad Bahrul Ulum (Unknown)



Article Info

Publish Date
30 Sep 2026

Abstract

Skin health is an important aspect of maintaining quality of life, while skin cancer requires early detection to support appropriate treatment. This study explores the application of Explainable Artificial Intelligence (XAI), particularly LIME and Eigen-CAM, to interpret the results of binary skin cancer classification into benign and malignant classes. Classification was performed using a transfer learning approach with ResNet50, VGG16, EfficientNetB0, and MobileNetV2 architectures on a dataset of 2,000 skin images, with an equal number of samples in both classes. Model performance was evaluated using 5-fold cross-validation to obtain more consistent performance estimates across the test data. The experimental results showed that ResNet50 achieved the highest accuracy of 86.90%, followed by VGG16 at 85.90%, MobileNetV2 at 84.90%, and EfficientNetB0 at 84.85%. Visualization using LIME and Eigen-CAM highlighted image regions that contributed to the model's predictions, providing additional insights into the basis of its classification decisions. These findings indicate that XAI can serve as an interpretative approach for improving the understanding of model predictions in binary skin cancer classification.

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Journal Info

Abbrev

stmsi

Publisher

Subject

Computer Science & IT Electrical & Electronics Engineering

Description

Sistemasi adalah nama terbitan jurnal ilmiah dalam bidang ilmu sains komputer program studi Sistem Informasi Universitas Islam Indragiri, Tembilahan Riau. Jurnal Sistemasi Terbit 3x setahun yaitu bulan Januari, Mei dan September,Focus dan Scope Umum dari Sistemasi yaitu Bidang Sistem Informasi, ...