<![CDATA[PT.MJF is a pharmaceutical company engaged in livestock pharmaceuticals and produces several products. One of its sub-units is engaged in maintenance, producing vaccines, and sterilizing pharmaceutical equipment. Production activities in this sub-unit require a steam machine to sterilize livestock equipment; the machine is called an autoclave machine. The Autoclave-035 machine frequently experiences damage and malfunctions from 2019 to 2022, with a total of 41 breakdowns causing machine downtime. The purpose of this research is to find out the maintenance condition of PT.MJF and the effectiveness of the Autoclave-035 machine. The method used is Overall Equipment Effectiveness (OEE) and Six Big Losses. After conducting research, the average value of OEE is 91%. This result is good because it is above the world-class standard of 85%. It is known that the biggest losses that occur are reduced speed losses of 31.67% and equipment failure losses of 28.09% of the total losses. What causes the number of losses consists of machine, human, environmental, material, maintenance schedule, and energy factors. Machine and human factors are the most dominant factors.]]>
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