Smoking is a serious global health issue that contributes to various diseases and mortality. The World Health Organization (WHO) reports that the number of active smokers in Indonesia has reached 72,723,300 people and is projected to increase to 96,776,800 by 2025. Oral and dental health is an integral part of overall health, yet it is often overlooked in the context of smoking behavior. This study aims to determine the relationship between smokers’ level of knowledge and their oral and dental health status in Surutanga Subdistrict, Wara Timur District, Palopo City. The research employed a quantitative approach with a cross-sectional design. A sample of 35 adult smokers aged 20–40 years was selected using total sampling. Data analysis using the Spearman Rank test showed a P-value of 0.002 (P < 0.005), indicating a significant relationship between smokers’ knowledge level and their oral and dental health status. The majority of respondents had moderate knowledge (57.1%) and experienced dental caries (91.4%). It is recommended that future studies cover a broader area and include additional variables such as smoking behavior, toothbrushing frequency, and dietary habits that influence oral and dental health.
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