<![CDATA[Background: Acute asthma exacerbations cause bronchoconstriction that impairs respiratory mechanics and alveolar gas exchange, resulting in decreased peripheral oxygen saturation accompanied by compensatory tachypnea. This condition requires immediate management in the Emergency Department, where high concentration supplemental oxygen through a Non-Rebreathing Mask (NRM) is commonly used as an initial intervention. Objective: This study aimed to analyze and document changes in oxygen saturation and breathing frequency before and after oxygen administration using an NRM in asthmatic patients treated at the Emergency Department of RSUD dr. Soewondo Kendal. Methods: This study used a descriptive case study design involving five asthmatic patients with a pre-post intervention approach. Respiratory parameters including breathing frequency and oxygen saturation were measured through clinical assessment and pulse oximetry before and after NRM oxygen therapy according to clinical indications. Results: At baseline, all patients showed hypoxemia with oxygen saturation levels of 85-90% and breathing frequencies of 30-36 breaths per minute. After NRM therapy, oxygen saturation increased to 95% or higher and the average respiratory rate decreased by 8-9 breaths per minute, indicating improvement in oxygenation and reduced respiratory effort. Conclusion: The administration of supplemental oxygen using a Non-Rebreathing Mask is clinically effective as an initial intervention to correct hypoxemia and improve respiratory parameters in patients with acute asthma exacerbations in the Emergency Department.]]>
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