Jurnal Ilmu Pertanian Indonesia
Vol. 31 No. 4 (2026): Jurnal Ilmu Pertanian Indonesia

GC-MS Analysis of Kabau (Archidendron jiringoides) Pod Peel Extract and Its Effect on Erythrocytes and Leukocytes in Male Mice Induced by Lead

Elisa Nurma Riana (Department of Biology, Faculty of Sciences, Institute of Technology Sumatera, Lampung 35365, Indonesia)
Shafira Aulia (Department of Biology, Faculty of Sciences, Institute of Technology Sumatera, Lampung 35365, Indonesia)
Jeane Siswitasari Mulyana (Department of Biology, Faculty of Sciences, Institute of Technology Sumatera, Lampung 35365, Indonesia)
Iffa Afiqa Khairani (Department of Biology, Faculty of Sciences, Institute of Technology Sumatera, Lampung 35365, Indonesia)
Tirta Setiawan (Department of Data Science, Faculty of Sciences, Institute of Technology Sumatera, Lampung 35365, Indonesia)
Lisana Husna Imaniar (Department of Biology, Faculty of Sciences, Institute of Technology Sumatera, Lampung 35365, Indonesia)
Rizka Fatriani (Department of Biology, Faculty of Sciences, Institute of Technology Sumatera, Lampung 35365, Indonesia)
Hida Arliani Nur Anisa (Department of Biology, Faculty of Sciences, Institute of Technology Sumatera, Lampung 35365, Indonesia)



Article Info

Publish Date
14 Sep 2026

Abstract

An increase in free radicals in the body can result from continuous exposure to heavy metals such as lead (Pb). This condition can result in oxidative stress due to damage to cellular structures, including the lipid bilayer membrane, cellular proteins, and DNA. One approach to reduce such damage is the administration of exogenous plant-derived antioxidants, including kabau. This study aimed to determine the chemical compound profile contained in kabau pod peel extract and to evaluate its effects on erythrocytes and leukocytes in lead-induced mice. GC-MS analysis was conducted to identify the types of compounds present in the extract. An in vivo experiment was conducted with six groups: three control and three treatment groups. The GC-MS results showed that the abundant antioxidant compounds were 2,3-butanediol and 4H-pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl. The in vivo results indicated that administration of kabau pod peel extract did not significantly affect leukocyte and erythrocyte counts in the blood of mice exposed to lead acetate. Keywords: antioxidant, archidendron, blood cell, GC-MS, kabau

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Journal Info

Abbrev

JIPI

Publisher

Subject

Agriculture, Biological Sciences & Forestry

Description

Artikel yang dimuat meliputi hasil-hasil penelitian, analisis kebijakan, dan opini-opini yang berhubungan dengan pertanian dalam arti luas, seperti agronomi, ilmu tanah, hama dan penyakit tanamam, ilmu kehewanan, kedokteran veteriner, keteknikan pertanian, teknologi industri, teknologi pangan, ilmu ...