Journal of Pharmaceutical and Sciences.
JPS Volume 9 Nomor 3 (2026)

Efektivitas Small Frequent Feedings terhadap Frekuensi Mual dan Muntah pada Ibu Hamil dengan Hiperemesis Gravidarum di Klinik Pratama Vina, Kota Medan

Yonike Vita Raini Br Ginting (Sekolah Tinggi Ilmu Kesehatan Mitra Husada, Medan, Indonesia.)
Friza Novita Sari Situmorang (Sekolah Tinggi Ilmu Kesehatan Mitra Husada, Medan, Indonesia)
Srilina Br Pinem (Sekolah Tinggi Ilmu Kesehatan Mitra Husada, Medan, Indonesia)
Nayla Sahfitri (Sekolah Tinggi Ilmu Kesehatan Mitra Husada, Medan, Indonesia)
Sayidina Br Ginting (Klinik Pratama Vina, Medan, Indonesia)



Article Info

Publish Date
13 Sep 2026

Abstract

Background: Small frequent feedings (SFF) is a dietary approach intended to improve food tolerance in pregnant women experiencing nausea and vomiting. Objective: To assess changes in symptom severity following SFF at Vina Primary Care Clinic, Medan. Methods: A single-group pretest–posttest study included 36 pregnant women with a clinical diagnosis of hyperemesis gravidarum. The protocol prescribed six to eight small meals daily, supported by food diaries and WhatsApp monitoring. Symptoms were assessed on days 1 and 3 using the 24-hour Pregnancy-Unique Quantification of Emesis and Nausea (PUQE-24) scale. Paired scores were compared using the Wilcoxon signed-rank test. Results: Mean PUQE-24 scores decreased from 9.28 ± 3.248 to 6.83 ± 3.140, with a mean paired reduction of 2.44 points (Z = −5.103; p < 0.001; r = 0.85). Median scores decreased from 9.0 to 6.0. The proportion with mild symptoms increased from 25.00% to 61.11%, while the proportion with severe symptoms decreased from 22.22% to 8.33%. Scores decreased in 34 participants, remained unchanged in one, and increased by one point in one. Twenty participants (55.56%) met the reported adherence threshold. Conclusion: SFF accompanied by education and monitoring was associated with lower PUQE-24 scores during short-term observation. The uncontrolled design precludes causal attribution; controlled studies are needed before its specific effectiveness can be established.

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Journal Info

Abbrev

jps

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Description

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, ...