Faktor-Faktor yang Berhubungan dengan Kepatuhan Hemodialisis pada Pasien Penyakit Ginjal Kronik di Rumah Sakit Murni Teguh Medan Tahun 2025

Tiomsar Sianturi (Master of Public Health Study Program, Faculty of Pharmacy and Health Sciences, Sari Mutiara Indonesia University, Medan, Indonesia.)
Kesaktian Manurung (Master of Public Health Study Program, Faculty of Pharmacy and Health Sciences, Sari Mutiara Indonesia University, Medan, Indonesia.)
Janno Sinaga (Master of Public Health Study Program, Faculty of Pharmacy and Health Sciences, Sari Mutiara Indonesia University, Medan, Indonesia.)
Rahmat Alyakin Dachi (Master of Public Health Study Program, Faculty of Pharmacy and Health Sciences, Sari Mutiara Indonesia University, Medan, Indonesia.)
Frida Lina Tarigan (Master of Public Health Study Program, Faculty of Pharmacy and Health Sciences, Sari Mutiara Indonesia University, Medan, Indonesia.)

Journal of Pharmaceutical and Sciences.
JPS Volume 9 Nomor 3 (2026)

Background: Hemodialysis adherence requires sustained engagement with a demanding treatment regimen. Objective: To examine factors associated with adherence at Murni Teguh Memorial Hospital, Medan. Methods: This analytical cross-sectional study included 172 purposively selected patients. Adherence was assessed using a modified six-item End-Stage Renal Disease Adherence Questionnaire. Associations were examined using chi-square tests and multivariable logistic regression. Results: Overall, 115 patients (66.9%) were adherent. Education, knowledge, and family support were associated with adherence (all p < 0.001), whereas age, sex, and dialysis duration were not (p = 0.866, 0.357, and 0.212, respectively). Adherence was 92.6% with good family support and 5.9% with poor support. Family support was the only significant adjusted term (Exp[B] = 416.36; 95% confidence interval [CI], 43.08–4024.31); sparse discordant observations and the wide interval limited precision. A post hoc unadjusted Firth analysis yielded an odds ratio of 164.10 (95% CI, 51.86–694.10). Conclusion: Family support was strongly associated with self-reported adherence. Family-centered counseling merits evaluation, but the cross-sectional design and imprecise estimates preclude causal interpretation.