<![CDATA[Kurikulum saat ini menekankan pada penerapan pendekatan pembelajaran mendalam (deep learning), di mana proses belajar tidak hanya sekedar hafalan, melainkan memahami konsep secara mendalam. Namun, kenyataan yang terjadi menunjukkan kesenjangan. Murid masih banyak mengalami miskonsepsi pada materi kompleks seperti transpor membran. Penelitian ini bertujuan menghasilkan media slide PowerPoint interaktif berbasis learning cycle 5E (Engagement, Exploration, Explanation, Elaboration dan Evaluation) guna mengurangi miskonsepsi pada sub materi transpor membran, yang layak berdasarkan kevalidan, kepraktisan dan keefektifan. Selain itu, media PowerPoint yang dikembangkan juga mendukung SDG 4 dengan membantu menciptakan pembelajaran yang lebih berkualitas. Penelitian ini menerapkan model 4D (Define, Design, Development dan Disseminate). Kevalidan media PowerPoint diperoleh dari validasi para ahli dan guru biologi. Kepraktisan media PowerPoint diperoleh dari hasil observasi murid dan angket respon murid. Keefektifan media PowerPoint diperoleh dari hasil belajar murid melalui pretest dan posttest. Subjek penelitian ini berjumlah 32 murid kelas XI-H MA Negeri 4 Jombang. Hasil penelitian menunjukkan bahwa media PowerPoint memperoleh rata-rata validitas sebesar 98,4% dengan hasil sangat valid. Hasil kepraktisan berdasarkan observasi aktivitas murid memperoleh rata-rata sebesar 100% dan angket respon memperoleh rata-rata sebesar 99,69% dengan tingkatan sangat praktis. Hasil keefektifan dari pretest-posttest mendapatkan rata-rata pergeseran konsep dari miskonsepsi menjadi paham konsep sebesar 79,70% dengan kategori efektif serta penurunan miskonsepsi paling tinggi terjadi pada konsep proses osmosis yaitu dari 71,88% menjadi 6,25%. Hasil tersebut mengindikasikan bahwa media PowerPoint interaktif berbasis learning cycle 5E yang dikembangkan valid, praktis dan efektif untuk mengurangi miskonsepsi pada sub materi transpor membran. Kata Kunci: PowerPoint, Learning Cycle 5E, Miskonsepsi, Transpor Membran, Kualitas Pendidikan. The current curriculum emphasizes deep learning, focusing on understanding concepts rather than memorization. However, many students still experience misconceptions, especially in complex topics like membrane transport. This study aimed to develop an interactive PowerPoint slide media based on the 5E learning cycle (Engagement, Exploration, Explanation, Elaboration and Evaluation) to reduce misconceptions in the membrane transport subtopic and to examine its feasibility in terms of validity, practicality, and effectiveness. Additionally, the developed PowerPoint media supports SDG 4 by enhancing learning quality. The study employed the 4D development model (Define, Design, Develop, and Disseminate). The validity of the PowerPoint media was determined through validation by media experts, subject matter experts, and biology teachers, while its practicality was assessed through observations of student involvement and response surveys. Effectiveness was measured based on students’ learning outcomes obtained from pretest and posttest results. The research subjects consisted of 32 eleventh-grade students of class XI-H at MA Negeri 4 Jombang. The results showed that the PowerPoint media achieved an average validity score of 98.4% (very valid), practicality scores of 100% based on student activity observations and 99.69% based on student responses (very practical), and an average conceptual shift from misconception to correct understanding of 79.70% (effective). The greatest reduction in misconceptions occurred in the concept of osmosis, decreasing from 71.88% to 6.25%. Therefore, it can be concluded that the interactive PowerPoint media based on the 5E learning cycle is valid, practical, and effective in reducing misconceptions in the membrane transport subtopic Keywords: PowerPoint, 5E Learning Cycle, Misconceptions, Membrane Transport, Education Quality. ]]>
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