Spiritual care is an important component of holistic care for critically ill patients, yet nurses may encounter difficulties integrating it into clinical practice. This study examined the associations of nurses’ knowledge and motivation with spiritual care provision for critically ill patients at H. A. Sulthan Daeng Radja Bulukumba Regional Public Hospital. A descriptive correlational study with a cross-sectional design was conducted among 60 eligible nurses working in the Intensive Care Unit (ICU) and Emergency Department (ED), recruited using total sampling. Data were collected using study-specific questionnaires measuring knowledge, motivation, and self-reported spiritual care provision. Fisher’s exact test showed significant associations between knowledge and spiritual care provision (p = 0.018; OR = 4.69; 95% CI: 1.39–15.87) and between motivation and spiritual care provision (p = 0.012; OR = 10.73; 95% CI: 2.82–40.77). Nurses with good knowledge and strong motivation were more likely to report good spiritual care provision. Educational and institutional support may strengthen spiritual care practices, although further longitudinal or interventional studies are needed.
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