Pengaruh Waktu Pemberian Antibiotik Spektrum Luas terhadap Mortalitas Pasien Sepsis: Systematic Review

Reza Farelim Wardana (Universitas Muslim Indonesia)
Prema Hapsari Hidayati (Universitas Muslim Indonesia)
Risna Rajab (Universitas Muslim Indonesia)
Faisal Sommeng (Universitas Muslim Indonesia)
Muhammad Yusuf Sidang Amin (Universitas Muslim Indonesia)

Jurnal Medika Nusantara
Vol. 4 No. 3 (2026): Jurnal Medika Nusantara

Sepsis is a life-threatening condition caused by a dysregulated host response to infection. Although the early administration of broad-spectrum antibiotics is recommended, its impact on mortality remains inconsistent. This systematic review was conducted by searching PubMed, the Cochrane Library, and Scopus in accordance with the PRISMA guidelines.