<![CDATA[Background: Heat cured acrylic resin is the most commonly used denture base material due to its good aesthetic value, biocompatibility and affordability, with its mechanical properties includes surface roughness and transverse strength. 0.2% chlorhexidine is a mouthwash solution that affects the mechanical properties of acrylic resin. This study aimed to analyze the effect of immersion in 0.2% chlorhexidine on the surface roughness and transverse strength of heat-cured acrylic resin. Method: This laboratory experimental study used a pre-test and post-test design with 24 heat-cured acrylic resin samples divided into four groups consisting of six samples each. Samples measuring 65×10×3mm were immersed in distilled water and 0.2% chlorhexidine solution (50 mL) for 30 minutes and 2 hours. Surface roughness and transverse strength were tested using a surface roughness tester and a universal testing machine. Data were analyzed using One-Way ANOVA and Post-Hoc tests. Results: Surface roughness increased significantly (p0.05), especially in the 2-hour 0,2% chlorhexidine immersion group. Transverse strength decreased significantly after being immersed for 30 minutes and 2 hours. Conclusion: Immersion in 0.2% chlorhexidine for 2 hours increased surface roughness and decreased the transverse strength of heat-cured acrylic resin.]]>
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