<![CDATA[The Drug Information Service (PIO) is a service provided by pharmacists to deliver accurate, unbiased, and up-to-date information to healthcare professionals such as doctors, pharmacists, nurses, and patients. This study aims to assess the impact of PIO on the adherence level of hypertensive patients at the Tanjung Enim Public Health Center, Muara Enim Regency.The research utilized a quasi-experimental method with a Nonrandomized Control Group Posttest Design. Data were collected using the MMAS-8 questionnaire, with sampling conducted prospectively based on predetermined inclusion and exclusion criteria during April–May 2023. The data were then analyzed using the chi-square test. A total of 40 patients participated in the study. The findings indicated that 65% of hypertensive patients were male, while 35% were female. The age distribution showed that 42.5% were between 40–49 years old, and 12.5% were over 70 years old. Among patients who received PIO, 45% demonstrated high adherence, while 55% exhibited moderate to low adherence. In contrast, among those who did not receive PIO, only 10% had high adherence, whereas 90% showed moderate to low adherence. The chi-square test results yielded a p-value of 0.034 (<0.05), indicating that drug information services have a significant effect on the adherence level of hypertensive patients at the Tanjung Enim Public Health Center, Muara Enim Regency ]]>
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