<![CDATA[Abstract Hypertension is a condition characterized by a persistent increase in blood pressure of ?140/90 mmHg. Uncontrolled hypertension may lead to serious complications such as stroke, heart disease, kidney failure, and vascular disorders. In addition to pharmacological treatment, non-pharmacological nursing interventions such as Isometric Handgrip Exercise and Relaxation Music Therapy can be implemented to help reduce blood pressure through improved vascular function and relaxation of the autonomic nervous system. This study aimed to determine the effect of Isometric Handgrip Exercise and Relaxation Music Therapy on reducing blood pressure in Mrs. M with hypertension at Hermina Kemayoran Hospital. The study employed a case study design using the nursing process, including assessment, nursing diagnosis, planning, implementation, and evaluation. Data were collected through interviews, observation, physical examination, medical records, and literature review. The intervention was conducted for three consecutive days, from April 8–10, 2026. The results showed an improvement in the patient's condition after the intervention. Blood pressure decreased, complaints of headache and dizziness were reduced, the patient appeared more relaxed, and overall comfort improved. These findings indicate that the combination of Isometric Handgrip Exercise and Relaxation Music Therapy effectively supports blood pressure reduction in patients with hypertension. The study concludes that Isometric Handgrip Exercise and Relaxation Music Therapy are effective, safe, and simple non-pharmacological nursing interventions for reducing blood pressure in patients with hypertension. These interventions can be applied as complementary therapies to improve patient outcomes and quality of nursing care.]]>
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