Background: Patient safety incident reporting is important for identifying problems in healthcare delivery and supporting corrective actions. However, underreporting among nurses remains a concern and may be related to limited knowledge, attitudes, and compliance with reporting procedures. Mentorship combined with transformational leadership principles may support improvement in these areas. Objective: This study aimed to examine changes in nurses’ knowledge, attitudes, and compliance with patient safety incident reporting following a Transformational Leadership-Based Mentorship Program compared with routine practice. Methods: A quasi-experimental study using a non-equivalent control group pretest-posttest design was conducted among 40 nurses in the inpatient units of Hospital X. Total sampling was used, with 20 nurses in the intervention group and 20 in the control group. The intervention group participated in a two-week structured mentorship program involving discussion, coaching, practical guidance, case reflection, supervision, and feedback. The control group continued routine nursing practice. Data were collected using questionnaires measuring knowledge, attitudes, and compliance with patient safety incident reporting. Data were analyzed using the Wilcoxon signed-rank test and Mann-Whitney U test at a significance level of 0.05. Results: In the intervention group, mean knowledge scores increased from 30.90 to 45.60, attitudes from 30.00 to 43.73, and compliance from 28.90 to 44.70. Within-group changes were significant for all three outcomes (p<0.001). Posttest scores also differed significantly between the intervention and control groups for knowledge, attitudes, and compliance (p<0.001). Conclusion: The Transformational Leadership-Based Mentorship Program was associated with greater improvements in nurses’ knowledge, attitudes, and compliance with patient safety incident reporting than routine practice.
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