Objective: To investigate the prevalence of primary dysmenorrhea and its associated factors among female students in Yogyakarta Province, Indonesia. Methods: A cross-sectional study was conducted among female university students in Yogyakarta Province, Indonesia, in 2021. A total of 385 participants were recruited using a purposive sampling method. Data were collected through an online structured questionnaire administered via Google Forms. The questionnaire incorporated the International Physical Activity Questionnaire (IPAQ) along with researcher-developed items that had been validated and tested for reliability before use. Data were analyzed using univariate and bivariate analyses, with the chi-square test applied at a significance level of 5% (p < 0.05). Variables with significant associations were subsequently included in a multivariable logistic regression analysis.Results: Severe primary dysmenorrhea was the most prevalent category, affecting 44.2% of respondents. A maternal history of dysmenorrhea was significantly associated with both mild (AOR = 0.450; 95% CI: 0.249–0.813; p = 0.008) and severe primary dysmenorrhea (AOR = 2.425; 95% CI: 0.774–2.292; p < 0.001).* Among treatment-related factors, healthy food consumption showed the strongest association with mild primary dysmenorrhea (AOR = 0.570; 95% CI: 0.392–0.830; p = 0.003), whereas medication use was most strongly associated with severe primary dysmenorrhea (AOR = 2.645; 95% CI: 1.624–4.308; p < 0.001). Conclusion: Severe primary dysmenorrhea was the most common presentation among female students. A maternal history of dysmenorrhea was significantly associated with both mild and severe primary dysmenorrhea. Healthy food consumption and medication use were the treatment-related factors most strongly associated with mild and severe dysmenorrhea, respectively. Strengthening collaboration among mothers, adolescents, and healthcare providers may improve the management of primary dysmenorrhea. Keywords: associated factors, female students, primary dysmenorrhea, reproductive health
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