<![CDATA[Children injured during armed conflict are particularly vulnerable to infectious complications when trauma occurs in settings characterized by disrupted healthcare services, poor sanitation, malnutrition, and limited access to antimicrobial therapy. This report describes a 2-year-old Palestinian girl who sustained penetrating cranial trauma from shrapnel during an explosion in Gaza and subsequently developed a left frontoparietal brain abscess accompanied by multiple pustular skin lesions. Non-contrast computed tomography demonstrated a large intracranial abscess, which was treated by percutaneous aspiration and systemic antimicrobial therapy. Culture of the intracranial aspirate yielded coagulase-negative Staphylococcus (CoNS), whereas the cutaneous lesions yielded Staphylococcus aureus. The patient showed clinical improvement following systemic antibiotics and topical mupirocin. Follow-up imaging later demonstrated residual structural abnormalities requiring continued surveillance. The differing microbiological findings do not establish a direct causal relationship between the cutaneous infection and brain abscess; penetrating trauma and subsequent wound contamination remain plausible pathways. This case illustrates how resource constraints, disrupted referral systems, limited diagnostics, and restricted antimicrobial availability complicate the management of pediatric neurotrauma in humanitarian emergencies.]]>
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