This study aims to examine the effect of perceived organizational support and teamwork on employee performance through employee engagement at Muhammadiyah Ponorogo General Hospital. This research employed a quantitative approach. The sample consisted of 128 permanent inpatient nurses selected using a saturated sampling technique. Data were analyzed using Structural Equation Modeling (SEM) with the assistance of SmartPLS version 4.1.1.2. The results show that perceived organizational support does not have a significant effect on employee performance, while teamwork has a positive and significant effect on employee performance. Employee engagement also has a positive and significant effect on employee performance. Furthermore, perceived organizational support does not significantly influence employee engagement, whereas teamwork has a positive and significant effect on employee engagement. The mediation analysis indicates that employee engagement does not mediate the relationship between perceived organizational support and employee performance. However, employee engagement is able to mediate the effect of teamwork on employee performance. Based on these findings, strengthening teamwork is important to enhance employee engagement and improve nurse performance.
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