<![CDATA[Tooth loss can impair mastication, phonetics, aesthetics, and quality of life, necessitating restorations that restore function and maintain long-term clinical performance. Fixed dental prostheses (FDPs) made of lithium disilicate are increasingly used because of their favorable mechanical and aesthetic properties. However, evidence regarding the durability and longevity of lithium disilicate restorations varies according to material type, clinical conditions, and evaluation parameters. This literature review aimed to examine the clinical longevity of lithium disilicate crowns used in fixed dental prostheses based on survival rate, success rate, mechanical strength, wear resistance, marginal adaptation, bond strength, and restoration-related complications. A literature review was conducted using a systematic approach based on the PRISMA 2020 guidelines. Literature searches were performed in PubMed, ScienceDirect, DOAJ, MDPI, Garuda, and Google Scholar for articles published between 2020 and 2025. Five studies were included in the review. The findings demonstrated that lithium disilicate exhibited favorable flexural strength and wear resistance, with good mechanical stability following chewing simulation. Marginal adaptation remained within clinically acceptable limits, while bond strength and translucency supported restoration performance. Clinical studies also reported high survival and success rates over six years. In conclusion, lithium disilicate demonstrates favorable clinical longevity as a restorative material for fixed dental prostheses, offering a balance between mechanical durability, long-term clinical performance, and aesthetic outcomes.]]>
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