<![CDATA[Diarrhea remains a public health problem in Indonesia, including North Padang Lawas Regency. Based on local health data, 2,987 cases of diarrhea were recorded, indicating the need for prevention efforts involving active community participation. Diarrhea is influenced by various factors, including hygiene and sanitation practices, environmental conditions, and community participation. Community empowerment through advocacy, teamwork, communication, and assistance is one strategy that may strengthen diarrhea prevention. This study aimed to analyze the effect of community empowerment strategies on diarrhea prevention in the working area of Hutaimbaru Community Health Center, North Padang Lawas Regency, in 2026. This study employed an analytic survey with a cross-sectional design. The study population consisted of 2,235 people, with 100 respondents selected using purposive sampling. Data were analyzed using univariate analysis, bivariate analysis with the Chi-square test, and multivariate analysis using multiple logistic regression. The results showed significant associations between advocacy and diarrhea prevention (p = 0.000), teamwork (p = 0.001), communication (p = 0.002), and assistance (p = 0.000). All variables had a significant effect on diarrhea prevention (p < 0.05). Multivariate analysis indicated that assistance was the most dominant factor influencing diarrhea prevention, with an odds ratio (OR) of 35.174. Community empowerment strategies, including advocacy, teamwork, communication, and assistance, significantly influence diarrhea prevention in the working area of Hutaimbaru Community Health Center, North Padang Lawas Regency. Assistance was identified as the most dominant factor. Community health centers are encouraged to strengthen community empowerment activities to support sustainable diarrhea prevention.]]>
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