Jurnal SainHealth
Vol. 10 No. 2 (2026): September 2026

COMPARISON OF LEUKOCYTE COUNT AND TYPES, NEUTROPHIL-TO-LYMPHOCYTE RATIO (NLR), AND PLATELET-TO-LYMPHOCYTE RATIO (PLR) IN NORMAL PREGNANT WOMEN AND THOSE WITH PREECLAMPSIA: PERBANDINGAN JUMLAH DAN JENIS LEUKOSIT, NEUTROFIL LIMFOSIT RATIO (NLR), PLATELET LIMFOSIT RATIO (PLR) PADA IBU HAMIL NORMAL DAN PREEKLAMPSIA

Trisilia Taufik Putri (Universitas Maarif Hasyim Latif)
Martha Indah Widiyaningtiyas (Universitas Maarif Hasyim Latif)
Titik Sundari (Universitas Maarif Hasyim Latif)
Dheasy Herawati (Universitas Maarif Hasyim Latif)



Article Info

Publish Date
28 Sep 2026

Abstract

Preeclampsia is a serious problem that can occur during pregnancy, usually after 20 weeks. This condition involves high blood pressure and protein in the urine. The number of leukocytes, especially neutrophils, is significantly higher in severe preeclampsia compared to normotensive pregnancies. The Neutrofil Limfosit Ratio plays a role in identifying inflammation and tumor immunology and has been shown to influence the prognosis of chronic and acute inflammatory conditions. The Platelet Limfosit Ratio may be using to assess an progression of the condition and whether it is worsening or whether infection or inflammation is occurring. The purpose of this research were to compare the number and type of leukocytes, NLR, and PLR in normal and preeclamptic pregnant women at the Mega Medika Clinic in Kampungbaru, Nganjuk. This research were an cross-sectional studies with 30 normal and preeclamptic pregnant women each who met the inclusion and exclusion criteria. The variables in this research was the number and type of leukocytes, NLR values, and PLR values. The results of the Mann-Whitney test showed that there were significant differences in the number of leukocytes, eosinophils, stab neutrophils (p = 0.000), segmented neutrophils (p = 0.035), lymphocytes (p = 0.008), monocytes (p = 0.015), and NLR (p = 0.017) between normal and preeclamptic pregnant women (p <0.05). Meanwhile, there were no significant differences in basophils (p = 0.082) and PLR (p = 0.395; p> 0.05). The conclusion is that the number of leukocytes, NLR values & types of leukocytes (eosinophils, stab neutrophils, segmented neutrophils & lymphocytes) are different between normal and preeclamptic pregnant women. While PLR values & types of leukocytes (basophils) are not different between normal and preeclamptic pregnant women.

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Journal Info

Abbrev

sainhealth

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

Description

Jurnal SainHealth is a study journal in the field of science, health, and both of them. The journal is published by the Faculty of Health Sciences Universitas Maarif Hasyim Latif ...