Medical students face high academic demands that may trigger burnout and activate the Hypothalamic Pituitary Adrenal (HPA) axis, which may influence glucose regulation and increase inflammatory responses in the body. This study aims to analyze the association between burnout and fasting blood glucose (FBG) levels and erythrocyte sedimentation rate (ESR). It used cross-sectional design which involved 106 active students through simple random sampling. Burnout was assessed by using the Maslach Burnout Inventory Student Survey (MBI-SS). Moreover, FBG was measured by using spectrophotometer and ESR was measured by using the Westergren method. Bivariate analysis was conducted using the Chi-square test (p<0.05). The results show significant association between burnout level and fasting blood glucose (FBG) (p = 0.012), with the highest proportion of elevated FBG observed in the moderate burnout category (21.3%). In addition, significant associations are found between burnout and erythrocyte sedimentation rate (ESR) in females (p = 0.029) and males (p = 0.028), with the highest proportion of elevated ESR in the moderate burnout category (30.8% in females and 37.5% in males).The mean burnout level is categorized as moderate that is significantly associated with elevated fasting blood glucose (FBG) and erythrocyte sedimentation rate (ESR) in both male and female students.
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