Journal of Information System Exploration and Research
Vol. 4 No. 4: October 2026

Non-Invasive Anemia Screening Using Fingernail Images with EfficientNetV2-B0

Maulany Citra Pandini (Department of Software Engineering, Institut Teknologi Statistika dan Bisnis Muhammadiyah Semarang, Indonesia)
Nurul Huda (Department of Information Technology, Universiti Muhammadiyah Malaysia, Malaysia)



Article Info

Publish Date
11 Oct 2026

Abstract

Anemia is a prevalent health condition requiring timely detection for appropriate clinical management. Conventional diagnosis relies on blood-based examinations, which are invasive and may be less practical for rapid and accessible screening. These limitations highlight the need for non-invasive and automated approaches to support preliminary anemia screening. This study develops and evaluates a non-invasive automated anemia classification framework using fingernail images and EfficientNetV2-B0. A dataset of 4,260 fingernail images from anemia and non-anemia classes was used. The images were converted into RGB format and resized to a resolution of 224 × 224 pixels, normalized using ImageNet statistics, and augmented to improve robustness. EfficientNetV2-B0 was pre-trained on ImageNet and subsequently fine-tuned to perform binary classification. The model achieved 97.89% accuracy, 0.98 precision, 0.97 recall, 0.98 F1-score, and 0.99 ROC-AUC on the independent test set. These findings suggest that the proposed framework could support rapid and non-invasive automated anemia screening.

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Journal of Information System Exploration and Research is a journal that publishes and disseminates scientific research papers on information systems to a wide audience particularly within the information system ...