Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat
Vol. 10 No. 1 (2026): Juni

STUDI IN VIVO GEL FRAKSI ETIL ASETAT Aloe vera UNTUK PENYEMBUHAN LUKA BAKAR

Arief Rafsanjani (Hamzanwadi University)
Jeli Marlita (Univeristas Hamzanwadi)
Lindayanti Lindayanti (Univeristas Hamzanwadi)



Article Info

Publish Date
30 Jun 2026

Abstract

Aedes aegypti is the primary vector of dengue fever, a major public health concern worldwide. This study aimed to evaluate the larvicidal activity of ethanol extract of garlic peel (Allium sativum L.) and to analyze the effect of different extract concentrations on larval mortality. The extract was obtained using the reflux extraction method with 70% ethanol as the solvent. An experimental laboratory study was conducted by exposing third-instar A. aegypti larvae to various concentrations of the extract. Larval mortality was analyzed using probit analysis to determine the LC90 and LT90 values. Mortality observations were carried out at 30, 60, 120, 240, 480, 720, and 1440 minutes (24 hours) after treatment. Statistical analysis revealed significant differences in larval mortality among treatment groups (p < 0.05). LT50 and LT90 values were estimated using probit analysis and should be presented together with their 95% Confidence Intervals (CI) to indicate the precision of the estimates. The results demonstrated that the ethanol extract of garlic peel exhibited larvicidal activity, with larval mortality increasing as the extract concentration increased. The LC90 and LT90 values confirmed the effectiveness of the extract as a larvicidal agent. These findings suggest that garlic peel has the potential to serve as a safe, environmentally friendly, and sustainable plant-based larvicide for the control of Aedes aegypti populations

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Journal Info

Abbrev

jurnal_farmasindo

Publisher

Subject

Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

Description

The journal includes various fields of pharmaceuticals sciences such as: Pharmacy, Pharmacokinetics, Community and Clinical Pharmacy, Medical, Alternative medicines, Synthetic Organic Chemistry, Organic Chemistry of Natural Material, Biochemistry, Chemical Analysis, Microbiology, Tissue Culture, ...