<![CDATA[Neuroblastoma is a type of neuroendocrine cancer that is very dangerous, but can be cured if earlydetected and appropriate therapy. Center for Radioisotope and Radiopharmaceutical Technology BATANSerpong has been succeeded in making labelled compounds131I-MIBG for early detection of neuroblastomacancer. Iodine-131 (I-131)-MIBG was prepared by reacting 127I-MIBG sulfate and Na131I using CuSO4catalyst and reducing agent as sodium bisulphite, pH = 3-4 with CH3COOH.The solution was refluxed at atemperature of 1600C so that the resulting of 131I-MIBG labelled compound.The radiochemical purity of theproduct was tested by chromatographic, using whatman paper number 1 asstationary phase and the mobilephase containing of n.butanol liquid mixture: acetic acid: water (5: 2: 1), and radionuclide purity test usinggamma spectrometer. Radiochemical and radionuclide purity131I-MIBG (diagnosis) was carried outof99.72% ± 0.32 and 99.99% ± 0.00 respectively. The labelled compound 131I-MIBG (therapy) withradioactivity dose of 25 mCi / vial was obtained of radiochemical purity = 98.33% ± 0.53 and radionuclidepurity = 99.99% ± 0.00, whereas radiochemical purity and radionuclide purity of131I-MIBG (therapy) withradioactivity dose of 50 mCi / vial was obtained 98.83% ± 0.32 and 99.99% ± 0.00 respectively.]]>
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