<![CDATA[Streptococcus mutans is one of the microorganisms in the oral cavity that can cause cavities. Preventionthat can be done to avoid this disease with mouthwash that contains antiseptic. Alternative methods can bedeveloped by utilizing natural ingredients as the basic ingredients for making mouthwash. Fragrant pandanleaves (Pandanus amaryllifolius roxb) contain several active compounds including flavonoids, tannins, andalkaloids that have the potential to have antibacterial activity. This study aims to determine the value of theMinimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of pandan leafethanol extract against Streptococcus mutans bacteria. Fragrant pandan leaf extract was obtained bymaceration method using 70% ethanol solvent with various concentrations of 0.36%, 0.78%, 1.56%, 3.12%,6.25%, 12.5%, 25%, 50 %, and 100%. The determination of the MIC value was carried out by the liquiddilution method using a UV-Vis Spectrophotometer. While the determination of the value of MBC is done bythe Spread plate method. The results showed that the MIC value was at a concentration of 6.25% because itwas able to inhibit the growth of bacteria. While the MBC value is at a concentration of 25%, where at thatconcentration there are no bacterial colonies growing.]]>
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