<![CDATA[Acne affects all ages, from teenagers to adults, and is generally caused by bacteria. One of the main causes is Propionibacterium acnes, a gram-positive bacterium that lives in the skin and sebaceous follicles. Therefore, a natural solution for treating acne is gotu kola leaves, which are blended into a liquid roll-on face toner. Its flavonoids, tannins, saponins, and alkaloids act as antibacterial agents against Propionibacterium acnes. This study used a laboratory experiment. The results showed that the physical stability test of gotu kola leaf extract roll-on face toner (Centella asiatica (L.) urb) in formulation 1 (7.5%), formulation 2 (10%), and formulation 3 (12.5%) successfully withstood the test, maintained stable pH and viscosity, and exhibited no significant changes in color and odor upon storage. The gotu kola leaf extract roll-on face toner demonstrated very strong antibacterial activity against Propionibacterium acnes. Formula F3 (12.5%) had the largest inhibition zone diameter of 46.27 mm. However, based on ANOVA and post hoc tests, there was no significant difference between F2 (10%) and F3 (12.5%) compared to the positive control (sig > 0.05), so both formulas had comparable antibacterial effectiveness to the positive control.), so that both formulas had antibacterial effectiveness comparable to the positive control.]]>
Copyrights © 2026
