This study aims to analyze the effect of population and Gross Regional Domestic Product (GRDP) on poverty rates in Central Tapanuli Regency and Deli Serdang Regency during 2015–2024. A quantitative approach was employed using annual secondary data obtained from the Central Bureau of Statistics (BPS). Data were analyzed using multiple linear regression with EViews 8, including descriptive statistics, classical assumption tests, regression analysis, and hypothesis testing. The results show that population has no significant partial effect on poverty rates in either regency. GRDP has no significant effect in Central Tapanuli Regency but has a negative and significant effect in Deli Serdang Regency. Simultaneously, population and GRDP have no significant effect on poverty in Central Tapanuli Regency, whereas both variables significantly affect poverty in Deli Serdang Regency. The Adjusted R-squared values of 36.8% and 68.1% indicate the explanatory power of the independent variables in Central Tapanuli Regency and Deli Serdang Regency, respectively. These findings suggest that regional economic conditions and the relationship between economic output and poverty differ across the two regencies. GRDP appears to play a more prominent role in poverty reduction, particularly in Deli Serdang Regency. Therefore, local governments should promote inclusive economic growth, equitable development, and broader employment opportunities to improve community welfare and address regional poverty challenges. These strategies are expected to support more sustainable poverty alleviation efforts in both regencies.
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