Jurnal Ilmu Fisika
Vol 19 No 1 (2027): March 2027 (Forthcoming Issue)

Association of Tube Current-Time Product with Quantitative CT Image Quality in Bone Scan SPECT/CT

Fransischa Ramona (Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Andalas, Padang, 25163)
Afdhal Muttaqin (Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Andalas, Padang, 25163)
Yola Despriani (Nuclear Medicine Sub-Division, Department of Radiology, Radiotherapy, and Nuclear Medicine, Dr. M. Djamil Hospital, Padang, 25217)



Article Info

Publish Date
07 Nov 2026

Abstract

In bone scan single-photon emission computed tomography/computed tomography (SPECT/CT), the CT provides the anatomical reference for localizing scintigraphic findings. Because automatic exposure control (AEC) modulates the tube current–time product (mAs) according to patient attenuation, CT image quality may differ between examinations. This study quantified CT image quality and examined its association with AEC-selected mAs. CT datasets from 72 patients at the Nuclear Medicine Unit of Dr. M. Djamil Hospital, Padang, were analyzed retrospectively. Mean CT number and image noise were measured in a hepatic region of interest to derive signal-to-noise ratio (SNR), and data were evaluated using correlation and simple linear regression. Mean mAs, liver CT attenuation, image noise, and SNR were 58.35 ± 16.24, 56.66 ± 8.55 HU, 2.14 ± 0.49 HU, and 27.57 ± 6.59, respectively. Body mass index (BMI) correlated positively with mAs (r = 0.642, p < 0.001). Moderate negative correlations were found between mAs and SNR (r = −0.468, p < 0.001) and between mAs and liver CT attenuation (ρ = −0.444, p < 0.001), whereas mAs and image noise were not significantly associated (ρ = 0.209, p = 0.078). Under AEC, mAs alone cannot adequately explain variability in quantitative CT image quality.

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Journal Info

Abbrev

jif

Publisher

Subject

Astronomy Earth & Planetary Sciences Materials Science & Nanotechnology Physics

Description

Jurnal Ilmu Fisika (JIF) is a peer-reviewed open access journal on interdisciplinary studies of physics, and is published twice a year (March and September) by Department of Physics, Andalas University ...