<![CDATA[Nurse burnout is a critical issue in type C regional general hospitals in Indonesia, yet the literature remains inconsistent about whether it affects performance directly or through job satisfaction, and rarely tests burnout, work environment, and competence together in a single mediation model. This study aims to analyze the effects of these three determinants on nurse performance, both directly and through job satisfaction. A cross-sectional causal-explanatory design was applied to 198 nurses at Prof. Dr. M.A. Hanafiah SM Batusangkar Regional General Hospital using a census, with 192 respondents eligible for analysis. A five-point Likert questionnaire (51 items) was analyzed using PLS-SEM with 5,000-subsample bootstrapping. Burnout had a significant negative effect on job satisfaction (β = -0.476; p < 0.001), whereas work environment (β = 0.431; p < 0.001) and competence (β = 0.218; p < 0.001) had significant positive effects, together explaining 42.8 percent of the variance in job satisfaction. Job satisfaction significantly and positively affected performance (β = 0.220; p = 0.009), while the direct effect of burnout was not significant (β = -0.054; p = 0.459), indicating full mediation. Work environment and competence retained significant direct effects, with competence the strongest direct predictor (β = 0.306; p < 0.001). This study extends the Job Demands-Resources Theory by showing that mediation patterns differ across determinants, and recommends controlling burnout, improving job satisfaction, and strengthening nurses' clinical competence.]]>
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