JURNAL FARMASIMED (JFM)
Vol 9 No 1 (2026): Jurnal Farmasimed (JFM)

The Effect of Roselle Tea (Hibiscus Sabdariffa L.) on Prostaglandin F₂α Levels and Pain Intensity in Reproductive-Aged Women with Primary Dysmenorrhea

Mayang Citra Hariati (Institut Kesehatan Medistra Lubuk Pakam)
Dwi Handayani (Institut Kesehatan Medistra Lubuk Pakam)
Asti Pratiwi (Instiut Kesehatan Medistra Lubuk Pakam)



Article Info

Publish Date
30 Oct 2026

Abstract

Primary dysmenorrhea is a common reproductive health problem among women of reproductive age and is closely associated with increased prostaglandin F₂α production, which induces uterine contractions, vasoconstriction, ischemia, and menstrual pain. Roselle (Hibiscus sabdariffa L.) contains bioactive compounds with potential anti-inflammatory and antioxidant activities. Objective: This study aimed to evaluate the effect of roselle tea on prostaglandin F₂α levels and pain intensity in women of reproductive age with primary dysmenorrhea. Methods: A quasi-experimental two-group pretest-posttest design was conducted among 40 women with primary dysmenorrhea who were selected using purposive sampling and divided into intervention and control groups (n=20 each). The intervention group received 2 g of roselle tea brewed in 200 mL of warm water twice daily for three consecutive days, while the control group received 200 mL of warm water twice daily. Prostaglandin F₂α levels and pain intensity were measured at pretest, day 2, and day 3. Results: In the intervention group, mean prostaglandin F₂α levels decrease from 317.63±36.30 at pretest to 247.72±36.16 on day 2 and 183.62±47.33 on day 3 (p<0.001). Mean pain intensity also decreases from 2.35±0.489 to 2.00±0.324 and 1.10±0.718, respectively (p<0.001). The reductions are descriptively greater than those observed in the control group. Conclusion: Roselle tea shows potential as a complementary intervention for reducing prostaglandin F₂α levels and pain intensity in women with primary dysmenorrhea

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Journal Info

Abbrev

JFM

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal FARMASIMED (JFM) Volume I Nomor 1 Periode Mei - Oktober Tahun 2018. Jurnal ini memberikan ruang bagi akademisi, peneliti dan pengguna hasil penelitian dan pengabdian untuk mendiseminasikan, menginformasikan, mendiskusikan dan menggunakan hasil penelitian dan pengabdian sebagai upaya ...