Introduction: Rhabdomyolysis is the breakdown of skeletal muscle that releases intracellular contents, including creatine kinase, myoglobin, and potassium, into the circulation. It is commonly associated with trauma and may lead to acute kidney injury (AKI). Although high-volume fluid therapy is the standard treatment, management should be individualized according to the patient's condition. Case Report: A male patient presented with persistent pain in the left arm and leg after a motorcycle accident. Radiological examination showed fractures of the left radius and tibia accompanied by rhabdomyolysis. The patient underwent fasciotomy and backslab procedures, followed by intensive care monitoring with maintenance (low-volume) fluid therapy. His clinical condition improved, and he was discharged without further complications. Discussion: Rhabdomyolysis is a medical emergency with nonspecific clinical manifestations, making diagnosis challenging. It is confirmed by elevated creatine kinase levels and myoglobinuria. While aggressive fluid resuscitation is generally recommended, excessive fluid administration in patients with AKI may worsen fluid overload. Therefore, treatment should balance the benefits and risks based on individual clinical status. Conclusion: Low-volume fluid therapy may be considered in selected rhabdomyolysis patients with acute kidney injury when tailored to the patient's clinical condition.
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