Background: Evidence on cinnamon preparations does not establish the benefit of a locally prepared decoction. This study assessed changes in random blood glucose after a seven-day cinnamon decoction intervention among adults with diabetes mellitus. Methods: A one-group pretest–posttest study included 21 purposively selected adults aged 45–63 years at Kota Timur Primary Health Center, Gorontalo, Indonesia. Cinnamon decoction was administered once daily for seven days. Paired differences were assessed using the Shapiro–Wilk test, followed by a two-sided paired t-test. An exact Wilcoxon signed-rank test accounting for tied ranks was conducted as a sensitivity analysis. Results: Mean random blood glucose decreased from 360.62 (SD 102.22) to 304.62 (SD 136.87) mg/dL. The mean paired reduction was 56.00 mg/dL (95% CI 13.75–98.25), with t(20) = 2.765 and p = 0.012. The Shapiro–Wilk test of paired differences yielded W = 0.927 and p = 0.1225. Nineteen participants (90.5%) had lower follow-up glucose and two (9.5%) had higher glucose. The Wilcoxon sensitivity analysis also detected a difference (W = 33.00, exact p = 0.0028). Conclusion: Random blood glucose was lower after the intervention in most participants. The uncontrolled design and short follow-up do not establish clinical effectiveness or safety.
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