<![CDATA[Background: Adolescent HIV prevention literacy remains a school-health concern. This study assessed immediate knowledge and attitude changes following leaflet-supported education in Palu, Indonesia.Methods: A one-group pretest–posttest study included 77 randomly selected students from 96 eligible Grade 11 vocational students. Three approximately 50-minute sessions (18–20 March 2025) combined leaflets, lectures, and discussion. Knowledge and attitudes were assessed before and immediately after sessions. Paired t-tests compared baseline with the final assessment.Results: Knowledge increased from 12.34 to 20.49 (paired mean improvement 8.156; 95% CI 7.364–8.948; p < 0.001). Attitude scores increased from 64.41 to 81.81 (paired improvement 17.403; 95% CI 15.937–18.868; p < 0.001).Conclusion: The educational program was associated with improved immediate questionnaire scores.]]>
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