<![CDATA[Background: High school students are in adolescence, a transitional period between childhood and adulthood. This phase is characterized by heightened curiosity and increased susceptibility to health-risk behaviors, including smoking. Adolescent smoking remains a significant public health concern worldwide. This study examined changes in smoking-related knowledge and attitudes among students at SMA 22 Makassar after implementing the Brainstorming, Buzz Group, and Simulation (BBS) method. Methods: A quasi-experimental study involved 30 adolescent smokers at SMA 22 Makassar. Data were collected using questionnaires, and changes in smoking-related knowledge and attitudes were analyzed using the Wilcoxon signed-rank test. Result: The findings revealed statistically significant changes in students' smoking-related knowledge and attitudes following the BBS intervention (p < 0.001). Contribution for Practice: The findings provide preliminary evidence supporting the integration of brainstorming, buzz group discussions, and simulation into school-based health education programs. School nurses, teachers, and health promotion practitioners may consider these interactive methods to enhance adolescents' smoking-related knowledge, foster healthier attitudes, and strengthen smoking prevention education in schools.]]>
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