Journal of Pharmaceutical and Sciences.
Vol 3 No 1 (2020): JPS Volume 3 Nomor 1 (2020)

UJI AKTIVITAS ANTIBAKTERI SEDIAAN OBAT KUMUR EKSTRAK ETANOL BUAH KAPULAGA (Amomum compactum Sol. ex Maton) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus DAN Streptococcus mutans

Vriezka Mierza (Unknown)
Sudewi Sudewi (Program Studi Farmasi, Fakultas Farmasi, Universitas Tjut Nyak Dhien)



Article Info

Publish Date
30 Jul 2020

Abstract

Local cardamom (Amomumcompactum Sol. Ex Manton) is able to inhibit the growth of fungi and cineol compounds. Local cardamom which is anti-fungal and contains antibacterial properties. This study aims to determine the ethanol extract of cardamom fruit which is formulated into a mouthwash that can inhibit the growth of bacteria Staphylococcus aureusand Streptococcus mutans at certain concentrations. The method of this research is to test the antibacterial activity of Staphylococcus aureus and Streptococcus mutansfrom the ethanol extract of cardamom mouthwash. The preparation was evaluated for physical stability of storage for 4 weeks, pH test and antibacterial test. All cardamom fruit ethanol extract mouthwash preparations have a good physical form and are stable. At 4 weeks of storage, do not have the appropriate pH and antibacterial activity of cardamom fruit ethanol extract mouthwash against Staphylococcus aureus and Streptococcus mutans 2%, 4%, and 6% for Streptococcus mutans, the inhibition diameter was 9 mm, and 8 mm, while Staphylococcus aureus had the inhibition diameter 12 mm, 11 mm, and 10 mm, respectively. The results of this study concluded that the ethanol extract of cardamom fruit can be formulated into mouthwash with concentrations of 2%, 4%, and 6% which have moderate inhibition against Streptococcus mutans bacteria and have strong category inhibition against Staphylococcus aureus bacteria.

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Journal Info

Abbrev

jps

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Description

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, ...